In 1941, G. W. Beadle and E. L. Tatum provided the first definitive experimental evidence that individual genes are responsible for directing the synthesis of specific polypeptides.
My research investigates the molecular and statistical properties of adaptive evolution. The overarching goal of my work is to develop a robust, quantitative model of adaptive evolution at the molecular...
The general area of research interest in my lab is virus-host cell interactions concerning hepatitis C virus (HCV) and flaviviruses such as dengue (DENV) and Zika viruses (ZIKV)...
My research is directed toward understanding structures of protein-RNA complexes in order to learn how protein nucleic acid interactions lead to specific chemical or cellular functions.
In short, we study chemical structure and reactivity trying to understand what organic molecules are and what they are capable of. Most of our research is hypothesis-driven...
Natural products and their synthetic derivatives have historically provided a rich source of pharmaceutical drug leads. Inspired by the application(s) of...
Our research is highly interdisciplinary and relies on organic synthesis, polymer synthesis, organometallic catalysis, analysis of macromolecular structure, and polymer physics...
Proton-coupled electron transfer reactions play essential roles in a variety of aqueous and biological redox processes; however, the overall redox mechanisms can be quite complex...
The Roper laboratory develops new methods and techniques in order to investigate biological signaling. Our main biological interest is how the secretion and coupling of...
Our research focus lies in both the synthesis and characterization of new materials exhibiting novel or improved properties, using experimental as well as theoretical techniques.
My general research interest is in molecular structure-function relationships as applied to motility. The organizational level is that of large macromolecular complexes--the interface of single-particle...
Research in our lab is focused on the synthesis of new inorganic materials using molten fluxes as reaction media. Growth of magnetic phases, semiconductors, and hydrogen storage alloys is of
Deep into the periodic table the increasing effects of relativity, spin-orbit coupling, and the subtle rearrangement of frontier orbital energies challenges our ability to predict...
In this laboratory we bring together skills in nuclear magnetic resonance (NMR) spectroscopy, membrane and computational biophysics, and biomathematics.
The principle that guides my research is that biological macromolecules are chemicals and biological processes are chemical processes; we should be able to understand them...
We are interested in how important cellular decisions such as proliferation, growth and polarization are made during animal development. Dysregulation of these cellular processes are tightly associated with tumorigenesis and